Straizo is a minor character in JoJo's Bizarre Adventure Part I: Phantom Blood as one of Master Tonpetty's disciples and as an antagonist in Part II: Battle Tendency. In Phantom Blood, Straizo meets up with Jonathan Joestar and aids him in his quest to defeat Dio Brando. Later on, he adopted and raised Lisa Lisa, a child Jonathan's wife Erina had rescued from a sinking boat, tutoring her in the mystical art of Hamon. In Battle Tendency, he uses the Stone Mask to become a vampire and escape his aging, following his departure to New York to kill Joseph Joestar due to him being a threat to his newfound immortality.