Josephus (Ant. xiv. 3. § 2) relates, that Pompey marching south from his winter quarters, probably at or near Antioch, razed the fortress of Apamea in 64 BCE whence the city was annexed to the Roman Republic. In the revolt of Syria under Q. Caecilius Bassus, it held out against Julius Caesar for three years till the arrival of Cassius, 46 BCE. (Dio Cassius xlvii. 26–28; Joseph. The War of the Jews i. 10. § 10.) On the outbreak of the Jewish War, the inhabitants of Apamea spared the Jews who lived in their midst, and would not suffer them to be murdered or led into captivity (Josephus, The War of the Jews ii. 18, § 5). Destroyed by Chosroes I in the 7th century it was partially rebuilt and known in Arabic as Famia or Fâmieh; and destroyed by an earthquake in 1152. In the Crusades it was sti