Charles Mynn Thruston (1738–1812) was a Virginian who led a regiment in the Continental Army during the American Revolutionary War. Before the war, he was an influential leader from the Shenandoah Valley. He raised a company of infantry at the start of the conflict and later commanded an ad hoc battalion. He was wounded at Trenton in December 1776. George Washington asked him to recruit Thruston's Additional Continental Regiment in March 1777. At around the same time, Thruston was wounded and had his arm amputated. His regiment never achieved full strength and was absorbed by Gist's Additional Continental Regiment two years later.