Dr. Monica Quartermaine, MD is a fictional character on the ABC soap opera General Hospital. The character was originated in 1976 by Patsy Rahn, but has been portrayed by Leslie Charleson since 1977. She is a member of the wealthy Quartermaine family. Her various affairs and quarrels with her husband Alan were major stories on the show throughout the 1980s and 1990s. In her time on the show, Monica has battled breast cancer, dealt with the loss of three children, her son Jason Morgan's amnesia and decision to become a mob enforcer, and various other conflicts.