The USS Defiant (NX-74205), originally the USS Sao Paulo (NCC-75633), was a 24th century Federation Defiant-class starship operated by Starfleet. The Defiant was assigned to Deep Space 9 in the final weeks of the Dominion War. This starship was the third known Federation ship to bear the name Defiant, and the second ship of the Defiant-class to bear the name Defiant.