In 1995, 3D Realms announced a First-Person Shooter called Prey, to be released in 1998, about a troubled young Native American who is abducted by aliens, gets loose in their giant organic spaceship, and must tap into his spiritual powers to rescue his girlfriend. The big selling point of the game was portals; the ability to create rifts in space between any two points of a level. There was also a comic from the minds at Penny Arcade. Prey was also the name of a short-lived TV series, a Michael Crichton novel, a couple of movies... That Other Wiki tells you more.