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  • Tryptophan
  • Tryptophan
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  • An amino acid naturally existing in foods such as spinach, mushrooms, chicken, turkey, beef, pork, lamb, game, beans, and milk. Considered to be a sedative, tryptophan has been commonly used to treat anxiety, depression, insomnia, migraine headaches, and weight loss. Important as an element for good nutrition, this amino acid is often considered, although falsely, the reason a large turkey dinner makes a person tired and sleepy after eating. It is true it increases the production of serotonin, a natural hormone that works on the body as a calming or sleep inducing agent, but the levels are so small that the effect is very minimal.
  • In the Foldit Lua interface, the functions structure.GetAminoAcid and structure.SetAminoAcid use lowercase "w" for tryptophan. For more, see Tryptophan on wikipedia. Vijay Pande of Folding@home wrote a piece on tryptophan on his blog:
  • Tryptophan ist ein Medikament, das zum Beispiel bei der Behandlung einer Virus-Grippe eingesetzt wird. Doktor Pulaski behandelt einmal eine Grippeepidemie mit Tryptophan und einem Lysindestillat (TNG: ). Im englischen Original handelt es sich um einen einzigen Stoff namens Tryptophan-lysine distillate.
  • Mehr Informationen können gefunden werden unter Vijay Pande von Folding@home schrieb einen Blogeintrag (englisch) über Tryptophan:
  • Tryptophan is an essential amino acid. L-Tryptophan is the essential building block for many life-giving biomolecules, including structural proteins, enzymes and the neurotransmitters, serotonin and melatonin.
  • For many organisms (including humans), tryptophan is an essential amino acid. This means that it cannot be synthesized by the organism and therefore must be part of its diet. Amino acids, including tryptophan, act as building blocks in protein biosynthesis. In addition, tryptophan functions as a biochemical precursor for the following compounds (see also figure to the right): The disorders Fructose Malabsorption and Lactose intolerance causes improper absorption of tryptophan in the intestine, reduced levels of tryptophan in the blood
  • right|250pxL-Tryptophan ist eine essentiellen Aminosäure, welche eine Vorstufe zum Neurotransmitter Serotonin darstellt und als Antidepressivum und Hypnotikum eingesetzt wird. Künstliches Serotonin ist für diesen Zweck ungeeignet, da es die Blut-Hirn-Schranke nicht passieren kann. Die schlaffördernde Wirkung geht darauf zurück, das Serotonin selbst wieder eine Vorstufe zum Schlaf-Hormon Melatonin ist. Tryptophan ist in Deutschland als apothekenpflichtiges Medikament erhältlich, kommt aber auch in einige Lebensmittel, wie etwa Kakaopulver, vor.
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abstract
  • An amino acid naturally existing in foods such as spinach, mushrooms, chicken, turkey, beef, pork, lamb, game, beans, and milk. Considered to be a sedative, tryptophan has been commonly used to treat anxiety, depression, insomnia, migraine headaches, and weight loss. Important as an element for good nutrition, this amino acid is often considered, although falsely, the reason a large turkey dinner makes a person tired and sleepy after eating. It is true it increases the production of serotonin, a natural hormone that works on the body as a calming or sleep inducing agent, but the levels are so small that the effect is very minimal.
  • In the Foldit Lua interface, the functions structure.GetAminoAcid and structure.SetAminoAcid use lowercase "w" for tryptophan. For more, see Tryptophan on wikipedia. Vijay Pande of Folding@home wrote a piece on tryptophan on his blog:
  • Tryptophan ist ein Medikament, das zum Beispiel bei der Behandlung einer Virus-Grippe eingesetzt wird. Doktor Pulaski behandelt einmal eine Grippeepidemie mit Tryptophan und einem Lysindestillat (TNG: ). Im englischen Original handelt es sich um einen einzigen Stoff namens Tryptophan-lysine distillate.
  • Mehr Informationen können gefunden werden unter Vijay Pande von Folding@home schrieb einen Blogeintrag (englisch) über Tryptophan:
  • Tryptophan is an essential amino acid. L-Tryptophan is the essential building block for many life-giving biomolecules, including structural proteins, enzymes and the neurotransmitters, serotonin and melatonin.
  • For many organisms (including humans), tryptophan is an essential amino acid. This means that it cannot be synthesized by the organism and therefore must be part of its diet. Amino acids, including tryptophan, act as building blocks in protein biosynthesis. In addition, tryptophan functions as a biochemical precursor for the following compounds (see also figure to the right): * Serotonin (a neurotransmitter), synthesized via tryptophan hydroxylase. * Niacin is synthesized from tryptophan via kynurenine and quinolinic acids as key biosynthetic intermediates. * Auxin (a phytohormone) when sieve tube elements undergo apoptosis tryptophan is converted to auxins. The disorders Fructose Malabsorption and Lactose intolerance causes improper absorption of tryptophan in the intestine, reduced levels of tryptophan in the blood In bacteria that synthesize tryptophan, high cellular levels of this amino acid activate a repressor protein, which binds to the trp operon. Binding of this repressor to the tryptophan operon prevents transcription of downstream DNA that codes for the enzymes involved in the biosynthesis of tryptophan. So high levels of tryptophan prevent tryptophan synthesis through a negative feedback loop and, when the cell's tryptophan levels are reduced, transcription from the trp operon resumes. The genetic organisation of the trp operon thus permits tightly regulated and rapid responses to changes in the cell's internal and external tryptophan levels.
  • right|250pxL-Tryptophan ist eine essentiellen Aminosäure, welche eine Vorstufe zum Neurotransmitter Serotonin darstellt und als Antidepressivum und Hypnotikum eingesetzt wird. Künstliches Serotonin ist für diesen Zweck ungeeignet, da es die Blut-Hirn-Schranke nicht passieren kann. Die schlaffördernde Wirkung geht darauf zurück, das Serotonin selbst wieder eine Vorstufe zum Schlaf-Hormon Melatonin ist. Tryptophan ist in Deutschland als apothekenpflichtiges Medikament erhältlich, kommt aber auch in einige Lebensmittel, wie etwa Kakaopulver, vor. In einigen Legal Highs (Herbal Ecstasy, Happy Caps) kommt Tryptophan vor.