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Queen Mary I of England

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The whole disaster that was Queen Mary I started when Princess Catherine of Aragon's "precious" sick betrothed Prince Arthur died, and left a "healthier" "more manly" kid brother, Henry, behind to marry. Catherine, having always had the hots for this kid, immediately leapt upon the opportunity, allowing Henry to give her syphilis, and her to give it congenitally to her future daughter Mary I herself. Apparently, syphilis was spreading like a bull on beer in those days.

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The whole disaster that was Queen Mary I started when Princess Catherine of Aragon's "precious" sick betrothed Prince Arthur died, and left a "healthier" "more manly" kid brother, Henry, behind to marry. Catherine, having always had the hots for this kid, immediately leapt upon the opportunity, allowing Henry to give her syphilis, and her to give it congenitally to her future daughter Mary I herself. Apparently, syphilis was spreading like a bull on beer in those days. Due to her congenital syphilis, and other health problems of the day, little Mary could never stay healthy, which, making her eternally irritable, possessed her to take for granted all the gifts, riches, and territories that King Henry VIII bestowed upon her. Some historians say Henry was still a "good guy", at this stage, but this matter is up for debate.