SM UB-110 was a German Type UB III submarine or U-boat in the German Imperial Navy () during World War I. She was commissioned into the German Imperial Navy on 23 March 1918 as SM UB-110. UB-110 was sunk 19 July 1918 by HMS Garry, ML 49, and ML 263. 23 crew members died in the event. UB-110 was raised on 4 October 1918 and broken up in England.