Midtown Gotham City located in the center of Gotham City. Almost all of Gotham's businesses are located in Midtown Gotham City. It is surrounded by four rivers: North is the River Monchant, South is the Gotham River, East is the East River and West is Queens River. Midtown Gotham City is also where Gotham Tower, Wayne Tower, Gotham Pier and the Prewitt Building are located.