In the near future, the Moon has been colonized and supports a station on its surface. A lunar shuttle known as Mayflower One is being rushed to launch from Houston. The head of the ground crew, The Sarge (Chuck Connors), does not like what is occurring, but he defers to the airline's management. A post-credit scene shows a screen that says "From Paramount Pictures: "Airplane III"". Murdock is then seen saying "That's exactly what they'll be expecting us to do!"