Khyber is one of the three main antagonists for the first two season arcs in Ben 10: Omniverse, along with Malware and Dr. Psychobos, and a supporting antagonist in subsequent seasons. He was hired by Dr. Psychobos to obtain DNA samples of predatory aliens for the Nemetrix. He later teams up with Albedo and helps him in his plans for revenge. He is allegedly the greatest huntsman in the galaxy, who has hunted down both sapient and non-sapient beings.