Deep Space 4 is a Federation deep space station and starbase near the Typhon Expanse. Around 2372, DS4 became a sector hub for renewed Starfleet interest in the Typhon Expanse region and exploration beyond the Expanse. Per Last Unicorn Games' RPG, the station was constructed in 2352 on a "low-lying" (negative z-axis) edge of the Federation. In his search for the ancient humanoids DNA puzzle, Richard Galen wanted to get to DS4 on a Vulcan transport, and there gain passage to Caere on an Al-Leyan transport. (TNG: "The Chase")