| rdfs:comment | - Isane was born into the small Kiko clan, originating from Amegakure. At first, she was considered a disgrace to the clan, due to her inability to master genjutsu, but she soon became skilled in ninjutsu and the use of her Yin Release. Some years later, she showed up in Suishōgakure, seeking shelter there. It was while she was walking in the streets towards one of the shops that she was hit by Kameyō's carriage and rendered unconscious. Kameyō then rescued her, taking Isane to her home and treating her for her injuries.
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| abstract | - Isane was born into the small Kiko clan, originating from Amegakure. At first, she was considered a disgrace to the clan, due to her inability to master genjutsu, but she soon became skilled in ninjutsu and the use of her Yin Release. It was then that she became considered a prodigy, and eventually became good friends with Konan, Yahiko, and Nagato. Soon, she became an orphan, after her clan rushed into a battle and were slaughtered. Konan began to take care of her, bringing her back to the Ame Orphans hideout. She was present when they encountered the Sannin, which explains Tsunade's surprise upon seeing her at the Five Kage Summit. However, she departed shortly before Jiraiya taught the orphans ninjutsu, as she was afraid of being discovered by anyone, especially leaf ninja. Some years later, she showed up in Suishōgakure, seeking shelter there. It was while she was walking in the streets towards one of the shops that she was hit by Kameyō's carriage and rendered unconscious. Kameyō then rescued her, taking Isane to her home and treating her for her injuries. When Isane awoke, Kameyō asked her if she would join an elite squad and that if she did, Kameyō would provide her with food, shelter, and care. Isane agreed and eventually was introduced to and partnered with Kazuko.
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